Hot News

June 2016


Congratulations to Alex Thompson for being awarded an NIH fellowship that will support him for the next two years!

February 2016


Allie Walker predicts the Oscars better than anyone else! Click here to read the write-up in YaleNews. Click here to see her interview on WTNH.

August 2015


Elissa Hobert accepts a postion at Moderna. Congratulations Elissa!

June 2015  

Congratulations to Rebecca and Amy on their most recent paper in Chemistry & Biology "Growth factor identity is encoded by discrete coiled coil rotamers in the EGFR juxtamembrane region" Well done!!

May 2015


Congratulations to Melissa and Amy on their most recent paper in J. Am. Chem. Soc. "Structural Differences between Wild-type and Double Mutant EGFR Modulated by Third-Generation Kinase Inhibitors" Read the press release here.

April 2015


The Schepartz lab congratulates Alanna on being named the 2015-2016 recipient of the Wheland Award. Click here to read the write-up in YaleNews.

February 2015


Congratulations to Jonathan and Angela on their most recent paper in J. Am. Chem. Soc.: "Fluorescence correlation spectroscopy reveals highly efficient cytosolic delivery of certain penta-arg proteins and stapled peptides"

September 2014


Congratulations to Jon and Mike on their most recent paper in J. Am. Chem. Soc.: "Positive allostery in metal ion binding by a cooperatively folded β-peptide bundle"

September 2014


Congratulations to Julie Kuroda-Lanselle Sinclair on her second first author paper in 2014!!

July 2014  

Congratulations to Julie and Beth on their most recent paper in J. Am. Chem. Soc.: "Inhibiting epidermal growth factor receptor at a distance". For details, click here.

July 2014


Congratulations to Roman and Alex on the first paper of the 'super-resolution' team in Angew. Chem. entitled "Super-resolution imaging of the golgi in live cells with a bioorthogonal ceramide probe"...tagged as a 'hot paper' no less.

June 2014


Congratulations to Seth Alexander, who is now Dr. Seth Alexander, after a successful thesis defense!

June 2014


We are all overjoyed to congratulate Seth Alexander on the upcoming publication of his paper in Organic Letters. Congratulations Seth!

June 2014


Thank you to the lab for putting eyelashes on Alanna's car. She loves them!!

May 2014


Schepartz lab welcomes two new graduate students, Alex Thompson (from Hamilton College) and John Shen (from Brandeis University).

May 2014


Congratulations to Julie Lanselle on being nominated to participate in this year's AbbVie Scholars Symposium, to be held at AbbVie's Corporate Headquarters in North Chicago, Illinois on July 31, 2014! Julie will present a poster entitled, "Stapled Peptides as Allosteric Modulators of Epidermal Growth Factor Receptor Activitiy".

May 2014  

Congratulations to Pam Wang on the publication of her most recent paper in J. Am. Chem. Soc. entitled "Design and high-resolution structure of a ß3-peptide bundle catalyst".

May 2014  

The Schepartz lab congratulates Alanna on being elected into the National Academy of Sciences!! Additional information may be found here.

May 2014  

Congratulations to Angela Steinauer for passing her qualifying exam and to Allison Walker for passing her antithesis exam! Both presentations were awesome!!

February 2014


Congratulations to Dr. Clarissa Melo Czekster for winning a Yale Postdoctoral Scholars Travel Fund Award. Clarissa will travel to the Biocatalysis GRC to present a poster entitled, "Exploring the catalytic flexibility of the bacterial ribosome".

January 2014


Betsy Smith accepts a tenure-track position at Elmira College.

January 2014


Jessica Goodman accepts a position at Biogen doing ALS research in the McCampbell Pharmacology group.

January 2014


Congratulations to Arikha Moses (Ph.D. 1997) for being named CSO of her second company, Galatea Surgical. Arikha's first company, TyRx, was just bought by Medtronic for 160 MM. Well done, Dr. Moses!

October 2013  

Congratulations to Beth Denton and Cody Craig for their paper entitled "A β-peptide agonist of the GLP-1 receptor, a class B GPCR"

September 2013  

Congratulations to Mike Melicher and John Chu for their paper entitled "A β-boronopeptide bundle of known structure as a vehicle for polyol recognition"

August 2012


Congratulations to Professors Andy Phillips and Alanna Schepartz, who were just awarded $2.5 million from the National Cancer Institute to investigate novel approaches to treat cancers previously considered “undruggable”. The highly competitive grant, to be distributed over five years at about $500,000 annually, comes through NCI’s “Provocative Questions” program. Schepartz and Phillips, in collaboration with Dylan Taatjes at the University of Colorado, seek to address question 18: Are there new technologies to inhibit traditionally ‘undruggable’ target molecules, such as transcription factors, that are required for the oncogenic phenotype? Click here to see the announcement in the Yale Bulletin.

July 2012


Elissa Hobert's paper in JACS entitled "Rewiring kinase specificity with a synthetic adaptor protein" highlighted in Angew. Chem.

May 2012


Schepartz lab welcomes two new graduate students, Julie Lanselle (from UC Berkeley) and Aaron Zwicker (from UW Madison).

March 2012


Congratulations to Elissa Hobert, now Dr. Hobert. Bravo!

December 2011


Congratulations to Jacob Appelbaum, now Dr. Appelbaum. Bravo!

November 2011


Congratulations to Alanna and John Chu for being awarded the Camille and Henry Dreyfus Postdoctoral Award in Environmental Chemistry!

September 2011


Check out our newest group photo!

September 2011


Alanna receives the 2012 Ronald Breslow Award for Achievement in Biomimetic Chemistry from the American Chemical Society. Click here to see the announcement in the Yale Bulletin.

March 2011


Cody's most recent paper, "Enhancing ß3-peptide bundle stability by design" is selected for the cover of ChemBioChem!

January 2011


Congratulations to Cody Craig for defending his thesis!

January 2011


Congratulations to Dan Fried for defending his thesis!

January 2011


Congratulations to Elissa Hobert for winning a travel grant to attend the International Conference on Biomolecular Engineering!!

December 2010


Congratulations to Tiffany Halo for defending her thesis!

June 2010


Alanna elected as a Fellow of the American Chemical Society!

May 2010


Alanna is elected as a member of the American Academy of Arts and Sciences (AAAS). Members of the AAAS represent innovative thinkers in every field and profession, including more than 250 Nobel and Pulitzer Prize winners. Click here to see the announcement in the Yale Bulletin.

April 2010


Alanna is awarded a highly coveted National Academies Keck Futures Initiative grant for a project entitled "Separate but equal: Design of orthogonal, functional environments within living mammalian cells"

March 2010


Former Schepartz Group graduate student Tanya Schneider has accepted a position as an Assistant Professor at Connecticut College. Congratulations, Tanya!

October 2009


Alanna is selected to present the Alexander M. Cruickshank Prize Lecture at the 2010 Gordon Research Conference on Biopolymers to be held at Salve Regina on June 6-11, 2010.

October 2009


Alanna is selected as the inaugural recipient of the ACS Chemical Biology Prize Lectureship. This award, bestowed by the ACS Division of Biological Chemistry, is designed to honor the contributions of a single individual who has had a major impact on scientific research in the area of Chemical Biology. The inaugural award will be presented at the 239th ACS National Meeting held March 21–25, 2010, in San Francisco.  For more information, visit

May 2009


Liz Harker's newest publication "In silico improvement of ß3-peptide inhibitors of p53-hDM2 and p53-hDMX", our most recent collaboration with the Jorgensen lab, is highlighted in Nature Chemistry.  Read the Highlight!

December 2008


Alanna is awarded Harvard University's 2008-2009 Frank H. Westheimer Prize in recognition of her outstanding research in chemistry and chemical biology. Check out the Press Release.

December 2008


Arjel Bautista receives a Bristol-Meyers Squibb Minority Chemist Fellowship Award.

July 2008


Doug Daniels accepts a position as a Research Scientist at Novartis Institute for BioMedical Research.

February 2008


Abby Hodges accepts a position as an Assistant Professor of Chemistry at Azusa Pacific University.

February 2008


James Petersson accepts a position as an Assistant Professor of Chemistry at the University of Pennsylvania.

January 2008


ß-peptide bundle structure chosen as one of the "most important advances in Chemistry during 2007" (wow). See the write-up:

November 2007


Danielle Guarracino receives a Travel Award from the ACS Division of Biological Chemistry to attend the ACS National Meeting in New Orleans. Check out her poster there!

November 2007


Doug Daniel's paper describing how to make miniaure proteins intrinsically cell permeable highlighted in Chemical & Engineering News.

November 2007


Nathan, Rachel, and Dan's paper on how to use biarsenicals as a fluorescent monitor of protein conformation and assembly chosen as a highlight of the recent literature (Editor's Choice) by Science magazine. Read the commentary. Read Yale's press release.

October 2007


Congratulations to Doug Daniels & James Petersson - High resolution structure of a ß-peptide bundle. (J. Am. Chem. Soc. 2007, 129, 1532-1533) now classified as a "HOT PAPER"! See for details.

October 2007


Congratulations to Joshua Kritzer, Olen Stephens, Danielle Guarracino, and Sam Reznik! Their review article entitled "ß-peptides as inhibitors of protein-protein interactions" was the most cited paper published in Bioorganic & Medicinal Chemistry during 2003-2006!

April 2007


Danielle Guarracino's poem, The Abl-Src Sonnet, is published in Yale's Literary and Arts Magazine, Palimpsest. Read the poem.

February 2007


Doug, James, and Jade's ß-peptide bundle paper is highlighted as "News of the Week" in Chemical & Engineering News. Read the press release. Read the HHMI News Announcement. Read the write-up in Chemistry World! Check out the article on the NIH NIGMS web-site! Read the article at Read the article in MIT's Technology Review. Read the article in Biomedical Beat.

January 2007


Doug Daniels, James Petersson, and Jade Qiu report the first high resolution structure of a cooperatively folded ß-peptide assembly. Check out the structure.

October 2006


Read about the new NFCR Center for Anti-Cancer Drug Design and Discovery, which will be led jointly by Alanna and Bill Jorgensen.

March 2006


Nathan Luedtke accepts a position as an Tenure-Track Assistant Professorship at the Institute of Organic Chemistry at the University of Zurich.

January 2006


Olen Stephens accepts a position as an Assistant Professor at Earlham College.

January 2006


James Petersson is awarded an NIH postdoctoral fellowship.

December 2005


Elizabeth de Martelly joins the group as an Editorial Assistant, Journal of the American Chemical Society. Welcome Elizabeth!

December 2005


Alanna named Associate Editor of JACS!

September 2005


Schepartz group moves into the top floor of the brand new Class of '54 Chemical Research Building!

June 2005


Alanna named a Fellow of the Royal Society of Chemistry!

June 2005


Schepartz lab expands with adding five new graduate students, two new postdoctorals, and 4 undergraduates in preparation for our move into the new Class of '54 Chemistry Research Building! Check out our group!

May 2005


Olen Stephens awarded an ACS Travel grant to present his research at the Fall 2005 ACS National Meeting.

April 2005


Doug Daniels awarded postdoctoral fellowships from both the American Cancer Society and the NIH to support his research in the group.

February 2005


Michelle Ferrara joins the lab as our new Senior Administrative Assistant.

September 2004


Jennifer Holtzman awarded another prestigious NSERC predoctoral fellowship to support her graduate work in the Schepartz lab.

March 2004


Jennifer Kohler (Ph.D. 2000) accepts position as Assistant Professor of Chemistry at Stanford!

October 2003


Alanna named a Fellow of the American Association for the Advancement of Science (AAAS) in honor of her “creative developments in bioorganic chemistry”

October 2003


Alanna discusses the Marie Curie Nobel Centennial Celebration on Connecticut Public Television

September 2003


Alanna named to Executive Board of Yale University Center for Genomics and Proteomics

April 2003


Dr. Anja Gemperli awarded a prestigious postdoctoral fellowship by the Swiss National Science Foundation

January 2003


Alanna joins the Editorial Advisory Board of the Journal of the American Chemical Society

September 2002


Alanna named a Howard Hughes Medical Institute Professor (press release)

September 2002


Jennifer Holtzman awarded prestigious NSERC pre-doctoral fellowship to support her graduate work in the Schepartz lab.

April 2002


Alanna one of 12 young women profiled in Chemical and Engineering News. (Article)

March 2002


Alanna wins the Agnes Fay Morgan Award

February 2002


Two Schepartz lab alumnae, Mary Kay H. Pflum and Arikha Moses, highlighted in Chemical and Engineering News

May 2001


Stacey Rutledge recipient of ACS Division of Medicinal Chemistry Predoctoral Fellowship

April 2001


Joshua Kritzer recipient of National Science Foundation Graduate Research Fellowship

April 2001


Scott Hart recipient of National Institute of Health Research Service Award

March 2001


Alanna Schepartz's essay from New Voices In Chemistry in Chemical and Engineering News